Here are some great articles on different ways to use YUPO by Sandrine Pelissier.

Mounting Yupo:
https://paintingdemos.com/how-to-mount-yupo-paper-on-board/
https://paintingdemos.com/mixed-media-flower-painting-on-yupo-paper-mounted-on-board/

Paintings on Yupo:
https://paintingdemos.com/a-series-of-three-paintings-for-the-anonymous-art-show/

Ink Wash on Yupo:
https://paintingdemos.com/autoportrait-5-an-experiment-in-ink-wash/


Media on Yupo:
https://paintingdemos.com/what-media-can-i-use-on-yupo-paper/
https://paintingdemos.com/comparative-chart-of-textures-on-yupo-paper-with-watercolors-acrylics-and-inks/


Acrylic on Yupo:
https://paintingdemos.com/painting-with-acrylics-on-yupo-paper/

Watercolor on Yupo:
https://paintingdemos.com/painting-with-watercolors-on-yupo-paper-a-few-techniques/

I am wondering if, over time, a watercolor on Yupo might
either
separate from the ground (Yupo paper)
or,
in climates with high humidity, the watercolors would liquefy and shift, run, etc.